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Pediatric renal transplantation in Southern Saudi Arabia: A single-center retrospective study
Hany M El Hennawy1, Ahmed Al Hashemy2, Abdullah S Al Faifi1, Omar Safar3, Mahmoud Ali Obeid4, Mohamed A Gomaa5, Ayed Alkhalaqi5, Mashair Babiker5, Abdelaziz A Abdelaziz6, Rawa M Al Humaid1, Mohammad F Zaitoun7, Khalid A AlAlsheikh5
1 Department of Surgery, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayt, Saudi Arabia
2 Department of Surgery, Section of Transplantation, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
3 Department of Urology, Armed Forces Hospitals Southern Region, Khamis Mushayt, Saudi Arabia
4 Department of Transplant Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia
5 Department of Pediatric Nephrology, Armed Forces Hospitals Southern Region, Khamis Mushayt, Saudi Arabia
6 Department of Nephrology, Armed Forces Hospitals Southern Region, Khamis Mushayt, Saudi Arabia
7 Department of Pharmacy, Armed Forces Hospitals Southern Region, Khamis Mushayt, Saudi Arabia
Correspondence Address:
Dr. Hany M El Hennawy
Department of Surgery, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayt - 101
Saudi Arabia
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/ijot.ijot_118_21
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Background: The outcome of pediatric renal transplantation (RT) has improved over the last decades. Aims and Objectives: To study the outcome of pediatric transplantation at our center including patient and graft survival, acute rejection, and surgical complications. Materials and Methods: A retrospective review of pediatric RT outcomes at the only transplant center in Southern Saudi Arabia. Results: between 11/2013 till 03/2020, 63 RT were performed in pediatric recipients 2 through 18 years of age (mean 11.7 ± 3.75) including 43 patients (68.2%) aged 14 and younger. Average BMI-height-age-z were 66.05 ± 6.65 percentile. 49 patients (77.7%) received kidneys from adult living donors (LD), 8(16%) were unrelated donors.41% had preemptive KT. The commonest known etiologies of ESRD were focal segmental glomerulosclerosis, Post Urethral valve, and dysplastic kidney (9.5% each). Thymoglobulin and Basiliximab were used as induction therapy in 37 (58.7%) and 26 (41.3%) patients respectively. With a mean follow-up of 80 months, 1-year and 5-year graft survival rates for LD and deceased donors were (97.2%, 86.4%) and (96.4%, 76%) respectively. 1-year and 5-year patients survival rates were 100%. Conclusions: pediatric renal transplantation outcome at our center, despite the low volume of cases, is encouraging.
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