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Year : 2021  |  Volume : 15  |  Issue : 4  |  Page : 354-356

Managing end-stage renal disease and live kidney transplant in a patient with hemophilia A: A case report and review of literature

1 Department of Nephrology, Mahatma Gandhi Medical College, Rajasthan, India
2 Department of Hematology, Mahatma Gandhi Medical College, Rajasthan, India

Correspondence Address:
Chandani Bhagat
B4/158 Safdarjung Enclave, New Delhi - 110 029
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijot.ijot_49_20

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Hemophilia A is caused by a genetic mutation affecting the levels of factor VIII in serum. With improvement in management and widespread availability of factor VIII, the life expectancy of hemophiliac patients has increased. The change in the history of hemophiliacs has led to the increased surge of chronic diseases in such patients. End-stage renal disease is rarely seen among hemophiliacs and institution of renal replacement therapy is controversial not only for the lack of literature but also differing opinions on protocols for factor VIII replacement. We describe here a case of a moderate hemophiliac A patient with end-stage renal disease undergoing renal replacement therapy initially hemodialysis and later on undergoing kidney transplantation. The patient successfully underwent live unrelated kidney transplant without any major complications and is currently healthy with good graft function. Patients with hemophilia A can successfully undergo renal replacement therapy under factor VIII cover.

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